Woolworths has decided not to stock CD singles due to declining sales.
The chain, the UK's biggest retailer of singles, attribute the death of the format to the rise in downloading.
Jim Batchelor, Woolworths' commercial director, said: "Digital downloading is now the true customer choice for listening and purchasing single music tracks.
"CDs are alive and well for album sales, but unfortunately the physical singles market is in terminal decline."
The store will continue to stock high profile singles, however, such as those released by the winners of television talent competitions like 'X Factor'.
The move will take place in August, and Woolworths have expanded their online store as a result.